2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N3919
    γ-Methoxyisoeugenol 63644-71-3 98%
    γ-Methoxyisoeugenol (Compound 5) is an anticoagulant agent that remarkably prolongs the thrombin time with a good dose-effect relationship at concentrations from 6.25 to 100 mM, but shows no significant differences in prothrombin time.
    γ-Methoxyisoeugenol
  • HY-N3931
    Gardneramine 34274-91-4 98%
    Gardneramine is an orally active alkaloid that acts like papaverine. Gardneramine has peripheral vascular diastolic effect, direct inhibition on myocardium and central inhibition. Gardneramine showed antihypertensive, vasodilatation and atrial inhibition effects in rabbit, dog and guinea pig models, respectively. Gardneramine also inhibits the movement of smooth muscle organs such as the stomach and intestines.
    Gardneramine
  • HY-N4209
    3α-Dihydrocadambine 54483-84-0 98%
    3α-Dihydrocadambine is a natural product isolated from the heartwoods of Anthocephalus cadamba.3α-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats.
    3α-Dihydrocadambine
  • HY-N4266
    Vinaginsenoside R8 156042-22-7 98%
    Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC50=25.18 μM).
    Vinaginsenoside R8
  • HY-N4309
    Lotusine 6871-67-6 98%
    Lotusine is a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn. Lotusine shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers.
    Lotusine
  • HY-N5006
    Guanfu base G 78969-72-9 98%
    Guanfu base G is an antiarrhythmic alkaloid isolated from Aconitum coreanum. Guanfu base G inhibits HERG channel current with an IC50 of 17.9 μM.
    Guanfu base G
  • HY-N5035
    Moscatin 108335-06-4 98%
    Moscatin inhibits AA-induced platelet aggregation in a concentration-dependent manner with IC50 values 37.2 μM .
    Moscatin
  • HY-N5036
    Ilexsaponin B3 109008-26-6 98%
    Ilexsaponin B3 has significant hypocholesterolemic activity.
    Ilexsaponin B3
  • HY-N5061
    Rotundatin 144506-16-1 98%
    Rotundatin is useful in inhibition of the aggregation of platelets induced by arachidonic acid and collagen.
    Rotundatin
  • HY-N5078
    Terrestrosin K 193605-07-1 98%
    Terrestrosin K, a steroidal saponin from Tribulus terrestris L., has potential to treat cardiovascular and cerebrovascular diseases.
    Terrestrosin K
  • HY-N5098
    Arenobufagin 3-hemisuberate 30219-16-0 98%
    Arenobufagin 3-hemisuberate is a natural compound as a cardiotonic steroid isolated from the skin of Japanese toad.
    Arenobufagin 3-hemisuberate
  • HY-N6050
    Lycorenine 477-19-0 98%
    Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities.
    Lycorenine
  • HY-N6245
    Daphylloside 14260-99-2 98%
    Daphylloside is an iridoid isolated from the aerial parts of Galium verum.
    Daphylloside
  • HY-N6256
    Ilexsaponin B2 108906-69-0 98%
    Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively.
    Ilexsaponin B2
  • HY-N6685
    3-Acetyldeoxynivalenol 50722-38-8 98%
    3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative, is a blood-brain barrier (BBB) permeable mycotoxin.
    3-Acetyldeoxynivalenol
  • HY-N6702
    Enniatin A 2503-13-1 98%
    Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes.
    Enniatin A
  • HY-N6881
    Gypenoside XIII 80325-22-0 99.13%
    Gypenoside XIII is belonging to the gypenosides. Gypenosides, extracted from Gynostemma pentaphyllum, have various pharmacological properties and protect against cardiovascular diseases, especially atherosclerosis.
    Gypenoside XIII
  • HY-N7044
    Vitexin arginine 98%
    Vitexin arginine is a c-glycosylated flavone, and is found in various medicinal plants species such as Ficus deltoid and Spirodela polyrhiza. Vitexin arginine has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects.
    Vitexin arginine
  • HY-N7326
    Latinone 79157-36-1 98%
    Latinone, a neoflavonoid isolated from Dalbergia cochinchinensis, has antiosteoporotic activity.
    Latinone
  • HY-N7328
    Lanatoside B 17575-21-2 98%
    Lanatoside B is a cardenolide that can be isolated from the leaves of Digitalis lanata.
    Lanatoside B
Cat. No. Product Name / Synonyms Application Reactivity